A groundbreaking innovation, La Grande Crème tackles all age-related skin concerns. EpigenActiv® “switches off” the genes that are involved in the process of skin ageing, to enable the ultimate regeneration. Its active ingredients improve the functional architecture of elastin and collagen fibers, giving a real “lifting” and anti-wrinkle effect. Skin on the face is strengthened, its contours are restructured and the complexion is clearer and more even.
Key Ingredients
Milk Thistle (Extract), EpigenActiv©, Mimosa Extract, White Tea Leaf Extract, Extract of young shoots of Watercress and pure Genistein derived from soybeans, Complex of Elderflower, Chestnut tree and Tropical almond leaf extracts, Complex of Matrikines, Muscle-relaxing peptide (Argireline), Carcinine, Peony extract, Skin-protecting oligosaccharide, Pichia Anomala (Extract), Wasabi (Extract), Grape juice extract enriched with δ-viniferin

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La Grande Crème
The Science
A total innovation in the world of professional cosmetics, La Grande Crème targets all age-related phenomena; it acts on the expression of genes involved in the cutaneous aging process to promote genuine cellular regrowth. Biologique Recherche identified and selected EpigenActiv©, a peptide that acts on EGF (or growth factor) receptors, essential to regenerate tissues and recycle degraded proteins
Instructions For Use
- Apply a small amount of product in the morning and/or at night to the entire face, neck and décolleté.
- Use this product after using the milk and the recommended P50 Lotion and the Sérums Authentiques from Biologique Recherche.
About Biologique Recherche
Founded in Paris by a biologist and physiotherapist duo, the brand has become a global gold standard in professional skincare. Beloved by the world’s top estheticians, Biologique Recherche delivers clinical, results-driven treatments with cold-pressed, fragrance-free formulas packed with the highest concentration of active ingredients.
The products truly work—you see and feel the difference. There’s a certain magic to Biologique Recherche, from its unmatched quality to the way it transforms skin. Its Skin Instant™ methodology redefined our approach to skincare, proving that skin is constantly evolving and should be treated accordingly.
Experience it yourself with a personalized consultation and facial, or discover the perfect home-care routine tailored to you.
Biologique Recherche Treatments will be available at Living Beauty Spring 2025.
