Crème Grand Millésime restores the skin’s radiance and helps prevent the signs of aging and fatigue; its regenerating and brightening active ingredients help promote cellular renewal to genuinely revitalize the skin. Dehydrated and tired epidermis is revitalized, brightened and smoothed.
Key Ingredients
Cellular oligopeptides, Reconstituted Natural Moisturizing Factor (NMF), Complex made from Hyaluronic Acid and Rhizobiumm, Complex made from Hyaluronic Acid and Rhizobium, Silk extract, Complex based on Myrrh, Myrtle and Onion, Cucumber extract, Witch Hazel and St. John’s Wort extracts, Mimosa Tenuiflora extract, Lactic acid, Citric acid (AHA), Salicylic acid (BHA)

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Crème Grand Millesime
The Science
Crème Grand Millésime restores the skin’s radiance and helps prevent the signs of aging and fatigue; its regenerating and brightening active ingredients help promote cellular renewal to genuinely revitalize the skin. Dehydrated and tired epidermis is revitalized, brightened and smoothed.
Instructions For Use
- Apply a small amount of product in the morning and/or at night to the entire face, neck and décolleté.
- Use this product after using the milk and the recommended P50 Lotion and the Sérums Authentiques from Biologique Recherche.
About Biologique Recherche
Founded in Paris by a biologist and physiotherapist duo, the brand has become a global gold standard in professional skincare. Beloved by the world’s top estheticians, Biologique Recherche delivers clinical, results-driven treatments with cold-pressed, fragrance-free formulas packed with the highest concentration of active ingredients.
The products truly work—you see and feel the difference. There’s a certain magic to Biologique Recherche, from its unmatched quality to the way it transforms skin. Its Skin Instant™ methodology redefined our approach to skincare, proving that skin is constantly evolving and should be treated accordingly.
Experience it yourself with a personalized consultation and facial, or discover the perfect home-care routine tailored to you.
Biologique Recherche Treatments will be available at Living Beauty Spring 2025.
